Registre National des Cancers de l’Enfant

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TU___NumTumeur_HS_z numtum TU__AnneeRegistre TU__Centre1_z TU__EtatFicheEnq TU_Z_Export_Neutralise TU_Z_FicheTumeur_EnExport Tdb Extension Ajout Cas en + de 201508  
S114804 114804 2007 PARIS-CURIE-OHP Remplie et validée True False BELOUAHRI 201601 _CodeTumeur num
H016547 16547 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508 S104616 104616
H017569 17569 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508 S119959 119959
H017644 17644 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508 S120095 120095
S117079 117079 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508 S120098 120098
S117083 117083 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508 S120168 120168
S117085 117085 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117131 117131 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117132 117132 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117137 117137 2008 PARIS-CURIE-OHP RAS et validée True False RAFFAINER 201508    
S117149 117149 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117152 117152 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117341 117341 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117852 117852 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117854 117854 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117857 117857 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117936 117936 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117940 117940 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S117948 117948 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119691 119691 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119766 119766 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119878 119878 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119886 119886 2008 PARIS-CURIE-OHP Dossier introuvable True False RAFFAINER 201508    
S119887 119887 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119893 119893 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119943 119943 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S119948 119948 2008 PARIS-CURIE-OHP Dossier introuvable True False RAFFAINER 201508    
S120072 120072 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S120420 120420 2008 PARIS-CURIE-OHP Remplie et validée True False RAFFAINER 201508    
S121761 121761 2008 PARIS-CURIE-OHP RAS et validée True False RAFFAINER 201508    
S121835 121835 2008 PARIS-CURIE-OHP RAS et validée True False RAFFAINER 201508    
S118683 118683 2007 PARIS-CURIE-OHP   False False      
S122138 122138 2009 PARIS-CURIE-OHP   False False      
H011719 11719 2004 PARIS-CURIE-OHP   False False      
H012317 12317 2005 PARIS-CURIE-OHP   False False      
H013043 13043 2005 PARIS-CURIE-OHP   False False      
H013890 13890 2006 PARIS-CURIE-OHP   False False      
H014214 14214 2006 PARIS-CURIE-OHP   False False      
H014218 14218 2006 PARIS-CURIE-OHP   False False      
H014504 14504 2006 PARIS-CURIE-OHP   False False      
H015132 15132 2006 PARIS-CURIE-OHP   False False      
H015135 15135 2007 PARIS-CURIE-OHP   False False      
H015137 15137 2007 PARIS-CURIE-OHP   False False      
H015899 15899 2007 PARIS-CURIE-OHP   False False      
H015901 15901 2007 PARIS-CURIE-OHP   False False      
H015903 15903 2007 PARIS-CURIE-OHP   False False      
H015908 15908 2007 PARIS-CURIE-OHP   False False      
H016293 16293 2007 PARIS-CURIE-OHP   False False      
H016297 16297 2007 PARIS-CURIE-OHP   False False      
H017137 17137 2008 PARIS-CURIE-OHP   False False      
H017972 17972 2009 PARIS-CURIE-OHP   False False      
H018040 18040 2009 PARIS-CURIE-OHP   False False      
H018080 18080 2009 PARIS-CURIE-OHP   False False      
H018640 18640 2009 PARIS-CURIE-OHP   False False      
H018804 18804 2009 PARIS-CURIE-OHP   False False      
H018940 18940 2008 PARIS-CURIE-OHP   False False      
H019020 19020 2010 PARIS-CURIE-OHP   False False      
H019038 19038 2010 PARIS-CURIE-OHP   False False      
H019042 19042 2009 PARIS-CURIE-OHP   False False      
H019146 19146 2010 PARIS-CURIE-OHP   False False      
H019169 19169 2010 PARIS-CURIE-OHP   False False      
H019991 19991 2010 PARIS-CURIE-OHP   False False      
H020034 20034 2009 PARIS-CURIE-OHP   False False      
H020426 20426 2010 PARIS-CURIE-OHP   False False      
H020999 20999 2011 PARIS-CURIE-OHP   False False      
S108513 108513 2005 PARIS-CURIE-OHP   False False      
S108519 108519 2005 PARIS-CURIE-OHP   False False      
S108530 108530 2005 PARIS-CURIE-OHP   False False      
S108532 108532 2005 PARIS-CURIE-OHP   False False      
S109966 109966 2005 PARIS-CURIE-OHP   False False      
S109967 109967 2005 PARIS-CURIE-OHP   False False      
S109970 109970 2005 PARIS-CURIE-OHP   False False      
S109979 109979 2005 PARIS-CURIE-OHP   False False      
S110099 110099 2005 PARIS-CURIE-OHP   False False      
S110103 110103 2005 PARIS-CURIE-OHP   False False      
S110112 110112 2005 PARIS-CURIE-OHP   False False      
S110170 110170 2005 PARIS-CURIE-OHP   False False      
S110173 110173 2005 PARIS-CURIE-OHP   False False      
S110196 110196 2005 PARIS-CURIE-OHP   False False      
S110452 110452 2005 PARIS-CURIE-OHP   False False      
S110658 110658 2006 PARIS-CURIE-OHP   False False      
S110672 110672 2006 PARIS-CURIE-OHP   False False      
S111652 111652 2006 PARIS-CURIE-OHP   False False      
S111768 111768 2005 PARIS-CURIE-OHP   False False      
S112637 112637 2006 PARIS-CURIE-OHP   False False      
S112642 112642 2006 PARIS-CURIE-OHP   False False      
S112647 112647 2006 PARIS-CURIE-OHP   False False      
S113104 113104 2005 PARIS-CURIE-OHP   False False      
S113144 113144 2006 PARIS-CURIE-OHP   False False      
S114696 114696 2006 PARIS-CURIE-OHP   False False      
S114702 114702 2006 PARIS-CURIE-OHP   False False      
S116427 116427 2007 PARIS-CURIE-OHP   False False      
S116429 116429 2007 PARIS-CURIE-OHP   False False      
S116446 116446 2007 PARIS-CURIE-OHP   False False      
S116465 116465 2007 PARIS-CURIE-OHP   False False      
S118521 118521 2007 PARIS-CURIE-OHP   False False      
S118673 118673 2007 PARIS-CURIE-OHP   False False      
S118674 118674 2007 PARIS-CURIE-OHP   False False      
S118694 118694 2007 PARIS-CURIE-OHP   False False      
S118737 118737 2007 PARIS-CURIE-OHP   False False      
S118754 118754 2007 PARIS-CURIE-OHP   False False      
S118805 118805 2007 PARIS-CURIE-OHP   False False      
S118810 118810 2007 PARIS-CURIE-OHP   False False      
S118894 118894 2006 PARIS-CURIE-OHP   False False      
S121827 121827 2009 PARIS-CURIE-OHP   False False      
S121908 121908 2009 PARIS-CURIE-OHP   False False      
S122157 122157 2009 PARIS-CURIE-OHP   False False      
S122160 122160 2009 PARIS-CURIE-OHP   False False      
S122445 122445 2010 PARIS-CURIE-OHP   False False      
S122446 122446 2010 PARIS-CURIE-OHP   False False      
S122453 122453 2010 PARIS-CURIE-OHP   False False      
S122455 122455 2010 PARIS-CURIE-OHP   False False      
S122519 122519 2010 PARIS-CURIE-OHP   False False      
S122520 122520 2010 PARIS-CURIE-OHP   False False      
S122526 122526 2010 PARIS-CURIE-OHP   False False      
S122527 122527 2010 PARIS-CURIE-OHP   False False      
S122546 122546 2010 PARIS-CURIE-OHP   False False      
S122547 122547 2010 PARIS-CURIE-OHP   False False      
S122567 122567 2010 PARIS-CURIE-OHP   False False      
S122568 122568 2010 PARIS-CURIE-OHP   False False      
S122569 122569 2010 PARIS-CURIE-OHP   False False      
S122574 122574 2010 PARIS-CURIE-OHP   False False      
S122584 122584 2010 PARIS-CURIE-OHP   False False      
S122585 122585 2010 PARIS-CURIE-OHP   False False      
S122630 122630 2010 PARIS-CURIE-OHP   False False      
S122639 122639 2010 PARIS-CURIE-OHP   False False      
S122781 122781 2009 PARIS-CURIE-OHP   False False      
S122786 122786 2009 PARIS-CURIE-OHP   False False      
S122789 122789 2009 PARIS-CURIE-OHP   False False      
S122794 122794 2009 PARIS-CURIE-OHP   False False      
S122798 122798 2009 PARIS-CURIE-OHP   False False      
S122836 122836 2009 PARIS-CURIE-OHP   False False      
S122837 122837 2009 PARIS-CURIE-OHP   False False      
S122945 122945 2009 PARIS-CURIE-OHP   False False      
S122946 122946 2009 PARIS-CURIE-OHP   False False      
S122947 122947 2009 PARIS-CURIE-OHP   False False      
S122948 122948 2009 PARIS-CURIE-OHP   False False      
S123040 123040 2009 PARIS-CURIE-OHP   False False      
S123044 123044 2009 PARIS-CURIE-OHP   False False      
S123045 123045 2009 PARIS-CURIE-OHP   False False      
S123084 123084 2009 PARIS-CURIE-OHP   False False      
S123088 123088 2009 PARIS-CURIE-OHP   False False      
S123104 123104 2009 PARIS-CURIE-OHP   False False      
S123118 123118 2009 PARIS-CURIE-OHP   False False      
S123240 123240 2010 PARIS-CURIE-OHP   False False      
S123241 123241 2010 PARIS-CURIE-OHP   False False      
S123244 123244 2010 PARIS-CURIE-OHP   False False      
S123253 123253 2010 PARIS-CURIE-OHP   False False      
S123304 123304 2010 PARIS-CURIE-OHP   False False      
S123693 123693 2010 PARIS-CURIE-OHP   False False      
S123694 123694 2010 PARIS-CURIE-OHP   False False      
S123695 123695 2010 PARIS-CURIE-OHP   False False      
S123704 123704 2010 PARIS-CURIE-OHP   False False      
S123706 123706 2010 PARIS-CURIE-OHP   False False      
S123707 123707 2010 PARIS-CURIE-OHP   False False      
S123728 123728 2010 PARIS-CURIE-OHP   False False      
S123730 123730 2010 PARIS-CURIE-OHP   False False      
S123734 123734 2010 PARIS-CURIE-OHP   False False      
S123747 123747 2010 PARIS-CURIE-OHP   False False      
S123748 123748 2010 PARIS-CURIE-OHP   False False      
S123750 123750 2010 PARIS-CURIE-OHP   False False      
S123838 123838 2009 PARIS-CURIE-OHP   False False      
S123845 123845 2009 PARIS-CURIE-OHP   False False      
S124070 124070 2010 PARIS-CURIE-OHP   False False      
S124120 124120 2009 PARIS-CURIE-OHP   False False      
S124840 124840 2007 PARIS-CURIE-OHP   False False      
S212465 212465 2011 PARIS-CURIE-OHP Remplie et validée False False      
S212474 212474 2011 PARIS-CURIE-OHP Remplie et validée False False      
S213965 213965 2004 PARIS-CURIE-OHP   False False      

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Diagnostic groups and subgroups AAPC(%) 95%CI p
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 0.1 [-0.4;0.7] 0.64
I.a Lymphoid leukemias 0.4 [-0.2;1.0] 0.23
I.b Acute myeloid leukemias -0.6 [-2.0;0.8] 0.38
II. Lymphomas and reticuloendothelial neoplasms -1.1 [-1.9;-0.2] 0.02
II.a Hodgkin lymphomas -0.3 [-1.6;0.9] 0.59
II.b Non-Hodgkin lymphomas (except Burkitt lymphomas) -1.2 [-2.7;0.3] 0.13
II.c Burkitt lymphomas -2.2 [-3.8;-0.5] 0.01
III. CNS and miscellaneous intracranial and intraspinal neoplasms 0.4 [-0.1;1.0] 0.13
III.a Ependymomas and choroid plexus tumors 0.8 [-1.0;2.6] 0.39
III.b Astrocytomas 0.5 [-0.4;1.4] 0.30
III.c Intracranial and intraspinal embryonal tumors -0.9 [-2.2;0.4] 0.17
III.d Other gliomas 0.1 [-1.4;1.7] 0.87
III.e Other specified intracranial and intraspinal neoplasms 2.0 [0.6;3.4]  <0.01
IV. Neuroblastomas and other peripheral nervous cell tumors -0.4 [-1.3;0.6] 0.48
IV.a Neuroblastomas and ganglioneuroblastomas -0.4 [-1.4;0.6] 0.40
V. Retinoblastomas -0.7 [-2.4;0.9] 0.40
VI. Renal tumors -0.2 [-1.3;1.0] 0.77
VI.a Nephroblastomas and other nonepithelial renal tumors -0.1 [-1.3;1.2] 0.92
VII. Hepatic tumors 2.0 [-0.8;4.9] 0.16
VII.a Hepatoblastomas 1.9 [-1.2;5.1] 0.23
VIII. Malignant bone tumors -0.4 [-1.7;0.9] 0.53
VIII.a Osteosarcomas -0.9 [-2.8;1.0] 0.35
VIII.c Ewing tumors and related bone sarcomas 0.7 [-1.2;2.7] 0.47
IX. Soft tissue and other extraosseous sarcomas -0.1 [-1.2;1.0] 0.80
IX.a Rhabdomyosarcomas 0.1 [-1.4;1.6] 0.88
IX.b Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms -0.3 [-4.4;3.9] 0.89
IX.d Other specified soft tissue sarcomas -0.5 [-2.4;1.5] 0.65
IX.e Unspecified soft tissue sarcomas 0.1 [-3.9;4.3] 0.95
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads -1.5 [-2.9;-0.1] 0.04
X.a Intracranial and intraspinal germ cell tumors -0.5 [-2.8;1.9] 0.67
X.b Malignant extracranial and extragonadal germ cell tumors -1.8 [-4.5;1.0] 0.21
X.c Malignant gonadal germ cell tumors -2.6 [-5.0;-0.1] 0.04
XI. Other malignant epithelial neoplasms and malignant melanomas 1.2 [-0.4;2.7] 0.14
XI.b Thyroid carcinomas -0.8 [-3.1;1.6] 0.53
XI.d Malignant melanomas -0.9 [-4.4;2.7] 0.62
XII. Other and unspecified malignant neoplasms 3.6 [-2.6;10.1] 0.26
All cancers (excluding LCH) -0.1 [-0.3;0.2] 0.72
Langherhans cell histiocytosis (LCH) -1.3 [-5.6;3.2] 0.56
All cancers (including LCH) -0.1 [-0.3;0.2] 0.69

AAPC: average annual percent change in incidence rate (estimated by Poisson regression model)

Temporal variations in the incidence rate of childhood cancer in mainland France, 2000-2014

    < 1 y    1 - 4 y   5 - 9 y   10 - 14 y  
Diagnostic groups and subgroups N/y IR N/y IR N/y IR N/y IR
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 28 35.7 222 71.5 150 38.3 116 29.4
Ia. Lymphoid leukemias 12 14.5 190 61.2 126 32.1 84 21.4
Ib. Acute myeloid leukemias 12 14.7 24 7.5 16 4.3 22 5.5
II. Lymphomas and reticuloendothelial neoplasms 0 1.1 24 7.5 54 13.8 106 27.1
IIa. Hodgkin lymphomas 0 0.0 4 1.3 16 4.0 66 16.8
IIb. Non-Hodgkin lymphomas (except Burkitt lymphomas) < 1 1.1 8 2.5 18 4.7 28 7.2
IIc.Burkitt lymphomas 0 0.0 12 3.7 20 5.1 12 3.0
III. CNS and miscellaneous intracranial and intraspinal neoplasms 30 38.9 142 46.0 146 37.2 124 31.8
IIIa. Ependymomas and choroid plexus tumors 6 8.4 18 6.1 10 2.4 10 2.6
IIIb. Astrocytomas 8 11.0 62 19.9 56 14.3 42 10.7
IIIc. Intracranial and intraspinal embryonal tumors 8 11.0 32 10.0 32 8.0 12 3.0
IIId. Other gliomas 2 2.1 14 4.5 24 6.1 18 4.6
IIIe. Other specified intracranial and intraspinal neoplasms 4 5.8 16 5.0 24 6.2 40 10.4
IV. Neuroblastomas and other peripheral nervous cell tumors 56 72.8 68 21.7 14 3.4 6 1.5
IVa. Neuroblastomas and ganglioneuroblastomas 56 72.5 68 21.6 12 3.3 4 1.0
V. Retinoblastomas 20 25.8 26 8.2 2 0.5 0 0.0
VI. Renal tumors 14 18.1 56 18.0 22 5.7 6 1.3
VIa. Nephroblastomas and other nonepithelial renal tumors 14 18.1 56 18.0 22 5.5 4 0.9
VII. Hepatic tumors 6 6.8 10 3.0 2 0.5 2 0.7
VIIa. Hepatoblastomas 6 6.6 8 2.8 2 0.4 < 1 0.2
VIII. Malignant bone tumors 0 0.5 4 1.5 22 5.5 56 14.4
VIIIa. Osteosarcomas 0 0.0 < 1 0.2 10 2.6 30 7.4
VIIIc. Ewing tumors and related bone sarcomas < 1 0.3 4 1.2 10 2.5 24 6.2
IX. Soft tissue and other extraosseous sarcomas 12 16.6 38 12.0 32 8.0 30 7.8
IXa. Rhabdomyosarcomas 4 5.3 28 9.1 18 4.7 10 2.6
IXb. Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 4 4.2 0 0.2 2 0.5 2 0.6
IXd. Other specified soft tissue sarcomas 4 5.3 8 2.3 8 2.1 16 3.8
IXe. Unspecified soft tissue sarcomas 2 1.8 2 0.4 2 0.7 4 0.8
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads 12 15.8 12 3.7 10 2.4 28 7.0
Xa. Intracranial and intraspinal germ cell tumors 2 1.6 4 1.4 6 1.5 14 3.5
Xb. Malignant extracranial and extragonadal germ cell tumors 10 12.4 4 1.5 < 1 0.1 2 0.4
Xc. Malignant gonadal germ cell tumors 2 1.8 2 0.8 4 0.8 10 2.7
XI. Other malignant epithelial neoplasms and malignant melanomas 2 2.1 6 2.1 12 3.0 44 11.4
XIb. Thyroid carcinomas < 1 0.3 2 0.7 4 0.8 16 4.2
XId. Malignant melanomas 0 0.0 2 0.5 4 0.8 6 1.7
XII. Other and unspecified malignant neoplasms 2 2.1 2 0.6 0 0.2 < 1 0.1
All cancers (excluding LCH) 180 236.3 608 195.8 464 118.3 518 132.5
Langherhans cell histiocytosis (LCH) 2 3.7 4 1.3 < 1 0.1 0 0.0
All cancers (including LCH) 182 240.0 612 197.1 464 118.4 518 132.5

Annual number of cases (N), age specific annual incidence rates (IR), mainland France 2010-2014.

    Incidence rate (/million)    
Diagnostic groups and subgroups N Crude ASR Cumulative Sex ratio
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 514 44 45.8 660 1.3
Ia. Lymphoid leukemias 410 35.1 36.7 526.7 1.3
Ib. Acute myeloid leukemias 72 6.2 6.4 93.7 1.2
Ic. Chronic myeloproliferative diseases 8 0.7 0.7 10.6 1.2
Id. Myelodysplastic syndromes and other myeloproliferative diseases 16 1.3 1.4 19.4 1.3
Ie. Unspecified and other specified leukemias 8 0.6 0.6 9.7 1.9
II. Lymphomas and reticuloendothelial neoplasms 184 15.7 14.7 235.6 1.9
IIa. Hodgkin lymphomas 86 7.3 6.6 109.2 1.4
IIb. Non-Hodgkin lymphomas (except Burkitt lymphomas) 56 4.7 4.5 70.6 1.8
IIc. Burkitt lymphomas 44 3.7 3.7 55.3 4.5
IId. Miscellaneous lymphoreticular neoplasms 0 0 0 0 -
IIe. Unspecified lymphomas 0 0 0 0 -
III. CNS and miscellaneous intracranial and intraspinal neoplasms 442 37.9 38.5 567.7 1.2
IIIa. Ependymomas and choroid plexus tumors 44 3.8 4.1 57.8 1.4
IIIb. Astrocytomas 168 14.4 14.7 215.6 1.1
IIIc. Intracranial and intraspinal embryonal tumors 82 7.0 7.4 106.0 1.6
IIId. Other gliomas 58 4.9 4.9 73.6 0.9
IIIe. Other specified intracranial and intraspinal neoplasms 86 7.3 7.0 108.8 1.4
IIIf. Unspecified intracranial and intraspinal neoplasms 6 0.4 0.5 7 1.2
IV. Neuroblastomas and other peripheral nervous cell tumors 142 12.1 13.9 184.1 1.2
IVa. Neuroblastomas and ganglioneuroblastomas 140 11.9 13.6 180.4 1.2
IVb. Other peripheral nervous cell tumors 2 0.2 0.2 3.7 0.8
V. Retinoblastomas 48 4.0 4.7 61.1 1.1
VI. Renal tumors 98 8.3 9.2 125.1 0.9
VIa. Nephroblastomas and other nonepithelial renal tumors 94 8.1 9.0 122.1 0.9
VIb. Renal carcinomas 2 0.2 0.2 4.0 0.4
VIc. Unspecified malignant renal tumors 0 0 0 0 -
VII. Hepatic tumors 20 1.6 1.8 24.8 1.3
VIIa. Hepatoblastomas 16 1.4 1.6 20.8 1.4
VIIb. Hepatic carcinomas 2 0.2 0.2 3.4 1.3
VIIc. Unspecified malignant hepatic tumors <1 0 0 0.3 0.0
VIII. Malignant bone tumors 82 7.1 6.5 106 1
VIIIa. Osteosarcomas 40 3.4 3.0 50.8 0.8
VIIIb. Chondrosarcomas 2 0.2 0.2 2.8 1.0
VIIIc. Ewing tumors and related bone sarcomas 38 3.2 3.0 48.6 1.1
VIIId. Other specified malignant bone tumors 2 0.2 0.2 2.9 0.8
VIIIe. Unspecified malignant bone tumors <1 0.1 0.1 1.4 3.0
IX. Soft tissue and other extraosseous sarcomas 112 9.5 9.8 143.6 1.2
IXa. Rhabdomyosarcomas 62 5.2 5.5 78.2 1.3
IXb. Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 8 0.7 0.7 10.5 1.4
IXc. Kaposi sarcomas 0 0 0 0 -
IXd. Other specified soft tissue sarcomas 34 2.9 2.9 44.0 1.1
IXe. Unspecified soft tissue sarcomas 8 0.7 0.7 10.9 0.9
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads 60 5.1 5.2 77.6 0.9
Xa. Intracranial and intraspinal germ cell tumors 26 2.1 2.1 32.2 2.3
Xb. Malignant extracranial and extragonadal germ cell tumors 16 1.4 1.6 20.9 0.6
Xc. Malignant gonadal germ cell tumors 18 1.5 1.4 22.5 0.4
Xd. Gonadal carcinomas <1 0.1 0.1 1.0 0
Xe. Other and unspecified malignant gonadal tumors 2 0.1 0.1 2.0 0
XI. Other malignant epithelial neoplasms and malignant melanomas 64 5.5 5.1 82.5 0.7
XIa. Adrenocortical carcinomas 6 0.5 0.5 7.1 1.1
XIb. Thyroid carcinomas 22 1.9 1.7 28.1 0.5
XIc. Nasopharyngeal carcinomas 6 0.4 0.4 6.5 2.6
XId. Malignant melanomas 12 1.0 0.9 14.5 1.2
XIe. Skin carcinomas 2 0.2 0.2 3.4 0.4
XIf. Other and unspecified carcinomas 18 1.6 1.4 23.4 0.5
XII. Other and unspecified malignant neoplasms 4 0.4 0.4 6.0 0.8
XIIa. Other specified malignant tumors 4 0.4 0.4 5.5 0.7
XIIb. Other unspecified malignant tumors <1 0 0 0.5 -
All cancers (excluding LCH) 1770 151.3 155.5 2270.9 1.2
Langherhans cell histiocytosis 8 0.6 0.7 9.4 0.7
All cancers (including LCH) 1778 151.9 156.2 2280.3 1.2

ASR: age standardised incidence rate

Annual number of cases (N), crude, age standardised and cumulative incidence rate of childhood cancer, and sex ratio (mainland France, 2010-2014).

5-year overall survival rates of childhood cancer in mainland France, by diagnostic groups and periods

Diagnostic groups and subgroups   2000-2004       2005-2009       2010-2014   P
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 83.0 [81.4-84.4] 87.1 [85.6-88.3] 86.0 [84.3-87.5] **
I.a Lymphoid leukemias 89.2 [87.7-90.5] 91.0 [89.6-92.2] 88.4 [86.6-90.0] *
I.b Acute myeloid leukemias 59.4 [54.3-64.1] 71.6 [66.4-76.2] 76.4 [71.1-80.8] **
II. Lymphomas and reticuloendothelial neoplasms 93.5 [91.7-94.8] 93.1 [91.3-94.6] 95.6 [93.9-96.8]  
II.a Hodgkin lymphomas 96.7 [94.5-98.0] 96.7 [94.3-98.0] 99.1 [97.3-99.7]  
II.b Non-Hodgkin lymphomas (except Burkitt lymphomas) 90.9 [87.0-93.7] 86.6 [82.0-90.1] 90.3 [85.9-93.4]  
II.c Burkitt lymphomas 91.4 [87.2-94.2] 95.1 [91.4-97.3] 96.0 [92.2-98.0]  
III. CNS and miscellaneous intracranial and intraspinal neoplasms 70.8 [68.8-72.8] 74.5 [72.6-76.4] 74.1 [72.0-76.1] *
III.a Ependymomas and choroid plexus tumors 62.2 [55.0-68.6] 77.1 [70.6-82.3] 83.3 [76.3-88.4] **
III.b Astrocytomas 86.9 [84.3-89.1] 87.9 [85.3-90.0] 83.2 [80.2-85.8] *
III.c Intracranial and intraspinal embryonal tumors 52.2 [47.3-56.9] 55.3 [50.3-6.0] 55.3 [49.4-60.9]  
III.d Other gliomas 34.9 [29.3-40.5] 39.7 [34.2-45.1] 39.2 [33.1-45.3]  
III.e Other specified intracranial and intraspinal neoplasms 93.5 [90.3-95.7] 95.8 [93.3-97.3] 94.8 [91.6-96.8]  
IV. Neuroblastomas and other peripheral nervous cell tumors 72.8 [69.3-75.9] 75.4 [72.0-78.4] 78.8 [75.0-82.2]  
IV.a Neuroblastomas and ganglioneuroblastomas 72.6 [69.1-75.8] 75.2 [71.8-78.2] 78.7 [74.7-82.1]  
V. Retinoblastomas 99.2 [96.8-99.8] 98.5 [96.0-99.4] 100.0 [-]  
VI. Renal tumors 91.8 [89.0-94.0] 93.0 [90.4-94.9] 94.1 [91.2-96.1]  
VI.a Nephroblastomas and other nonepithelial renal tumors 92.1 [89.2-94.2] 93.0 [90.3-94.9] 94.2 [91.3-96.2]  
VII. Hepatic tumors 83.1 [72.2-90.0] 79.1 [69.5-86.0] 82.6 [71.7-89.5]  
VII.a Hepatoblastomas 88.3 [77.1-94.3] 82.0 [71.6-88.9] 82.1 [71.1-89.2]  
VIII. Malignant bone tumors 74.6 [70.0-78.6] 75.6 [71.1-79.,5] 69.1 [63.0-74.5]  
VIII.a Osteosarcomas 72.9 [66.1-78.5] 74.5 [67.4-80.3] 63.1 [53.7-71.1]  
VIII.c Ewing tumors and related bone sarcomas 74.7 [67.4-80.6] 74.4 [67.6-79.9] 75.4 [66.7-82.1]  
IX. Soft tissue and other extraosseous sarcomas 69.1 [65.0-72.8] 73.5 [69.6-76.9] 73.5 [68.6-77.7]  
IX.a Rhabdomyosarcomas 67.4 [61.6-72.4] 74.2 [68.9-78.7] 77.1 [70.7-82.4]  
IX.b Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 74.4 [57.6-85.3] 80.0 [64.0-89.5] 76.9 [56.8-88.5]  
IX.d Other specified soft tissue sarcomas 72.5 [65-78.7] 71.3 [63.9-77.4] 67.9 [58.6-75.7]  
IX.e Unspecified soft tissue sarcomas 60.0 [43.2-73.3] 70.5 [53.9-82.1] 69.1 [49.5-82.3]  
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads 92.3 [89.0-94.7] 93.1 [89.8-95.4] 96.4 [93.5-98.1]  
X.a Intracranial and intraspinal germ cell tumors 91.9 [85.5-95.6] 94.0 [87.9-97.1] 96.5 [90.9-98.7]  
X.b Malignant extracranial and extragonadal germ cell tumors 92.3 [84.5-96.3] 85.2 [76.3-91.0] 96.2 [88.6-98.7]  
X.c Malignant gonadal germ cell tumors 95.7 [89.9-98.2] 98.3 [93.2-99.6] 98.6 [90.2-99.8]  
XI. Other malignant epithelial neoplasms and malignant melanomas 92.5 [88.6-95.1] 93.2 [89.5-95.7] 91.4 [86.7-94.5]  
XI.b Thyroid carcinomas 98.2 [93.0-99.5] 100.0 [-] 96.9 [86.7-99.3]  
XI.d Malignant melanomas 83.6 [70.8-91.1] 86.8 [72.8-93.8] 94.2 [83.1-98.1]  
XII. Other and unspecified malignant neoplasms 57.1 [28.4-78.0] 89.5 [64.1-97.3] 81.5 [57.9-92.6]  
All cancers (excluding LCH) 80.8 [79.9-81.6] 83.3 [82.4-84.0] 83.1 [82.1-84.0] **
Langherhans cell histiocytosis (LCH) 94.4 [79.6-98.6] 97.1 [80.9-99.6] 85.2 [68.0-93.6]  
All cancers (including LCH) 80.8 [80.0-81.6] 83.3 [82.5-84.1] 83.1 [82.1-84.0] **

p : pvalue of the logrank test (* <0.05; ** < 0.01)

{tabulizer:include style[gr.alterora.elemental_2_grey.css] id[tab_QtYF8F07IS]}

  Filles    Garçons     
Groupes diagnostiques %   %   P
I. Leucémies, syndromes myéloprolifératifs et myélodysplasiques 86.0 [84,6-87,2] 84.5 [83,3-85,7]  
II. Lymphomes et néoplasmes réticulo-endothéliaux 91.3 [89,2-93,0] 95.0 [93,8-95,9] *
III. Tumeurs du système nerveux central et diverses tumeurs intracrâniennes et spinales 72.7 [70,9-74,4] 73.5 [71,9-75,1]  
IV. Tumeurs du système nerveux sympathique 78.4 [75,5-81,0] 72.8 [69,9-75,5] *
V. Rétinoblastomes 99.0 [97,1-99,7] 99.1 [97,1-99,7]  
VI. Tumeurs rénales 94.4 [92,4-95,9] 91.2 [88,6-93,2]  
VII. Tumeurs hépatiques 80.7 [71,1-87,4] 83.7 [76,1-89,1]  
VIII. Tumeurs malignes osseuses 71.3 [67,0-75,1] 77.2 [73,4-80,6] *
IX. Sarcomes des tissus mous et extra-osseux 71.4 [67,5-74,9] 73.3 [70,1-76,2]  
X. Tumeurs germinales, trophoblastiques et gonadiques 94.0 [91,5-95,8] 92.9 [89,8-95,1]  
XI. Mélanomes malins et autres tumeurs malignes épithéliales 93.4 [90,6-95,4] 91.1 [87,1-94,0]  
XII. Autres tumeurs malignes 82.1 [62,3-92,1] 72.2 [45,6-87,4]  
Total 82.5 [81.8-83.1] 82.3 [81.6-83.0]  

Estimation des taux de survie à 5 ans des cancers de l'enfant en France métropolitaine sur la période 2000-2014, par groupe diagnostique et par sexe.

Diagnostic groups and subgroups    < 1 an    1-4 ans 5-9 ans  10-14 ans  
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 60.0 [54.9-64.7] 89.2 [88.0-90.2] 88.5 [87.0-89.8] 79.7 [77.5-81.6] **
I.a Lymphoid leukemias 52.3 [44.1-59.8] 93.6 [92.6-94.5] 90.8 [89.2-92.1] 83.5 [81.1-85.7] **
I.b Acute myeloid leukemias 64.4 [56.3-71.3] 63.2 [57.8-68.2] 81.1 [75.3-85.7] 65.7 [59.9-70.8] **
II. Lymphomas and reticuloendothelial neoplasms 90.9 [50.8-98.7] 92.1 [88.5-94.6] 94.2 [92.4-95.6] 94.1 [92.8-95.2]  
II.a Hodgkin lymphomas - [-] 100.0 [-] 98.3 [95.5-99.4] 96.9 [95.5-97.9]  
II.b Non-Hodgkin lymphomas (except Burkitt lymphomas) 90.0 [47.3-98.5] 86.1 [78.8-91.0] 89.4 [85.1-92.5] 89.9 [86.5-92.5]  
II.c Burkitt lymphomas 100.0 [-] 95.4 [90.7-97.8] 95.3 [92.4-97.2] 90.3 [85.3-93.7]  
III. CNS and miscellaneous intracranial and intraspinal neoplasms 62.1 [57.3-66.6] 70.8 [68.7-72.7] 71.3 [69.2-73.2] 80.5 [78.5-82.4] **
III.a Ependymomas and choroid plexus tumors 71.0 [60.0-79.5] 65.1 [58.6-70.8] 80.1 [71.5-86.4] 86.5 [78.5-91.6] **
III.b Astrocytomas 80.6 [72.4-86.6] 93.6 [91.6-95.1] 81.7 [78.7-84.3] 82.2 [78.8-85.1] **
III.c Intracranial and intraspinal embryonal tumors 25.0 [17.3-33.4] 36.7 [32.2-41.2] 67.5 [62.6-71.9] 79.1 [72.7-84.1] **
III.d Other gliomas 74.9 [55.9-86.6] 42.5 [35.8-49.1] 25.4 [20.8-30.2] 45.4 [39.1-51.4] **
III.e Other specified intracranial and intraspinal neoplasms 83.8 [70.0-91.6] 93.9 [89.7-96.4] 95.0 [92.2-96.8] 96.3 [94.2-97.7] **
IV. Neuroblastomas and other peripheral nervous cell tumors 90.2 [87.8-92.0] 66.8 [63.6-69.7] 62.5 [55.4-68.7] 65.3 [52.3-75.5] **
IV.a Neuroblastomas and ganglioneuroblastomas 90.2 [88.0-92.1] 66.6 [63.5-69.6] 62.7 [55.6-69] 55.8 [41.1-68.3] **
V. Retinoblastomas 99.4 [97.5-99.8] 98.9 [97.0-99.6] 100.0 [-] 100.0 [-]  
VI. Renal tumors 89.3 [84.2-92.8] 94.1 [92.3-95.5] 93.2 [89.6-95.6] 88.1 [76.7-94.2] *
VI.a Nephroblastomas and other nonepithelial renal tumors 89.3 [84.2-92.8] 94.1 [92.3-95.5] 93.4 [89.6-95.9] 88.9 [73.0-95.7] *
VII. Hepatic tumors 87.7 [76.8-93.6] 86.4 [79.0-91.3] 71.8 [49.4-85.6] 58.9 [40.2-73.6] **
VII.a Hepatoblastomas 87.5 [76.5-93.5] 86.7 [79.2-91.6] 70.6 [43.1-86.6] 44.4 [13.6-71.9] **
VIII. Malignant bone tumors 80.0 [20.4-96.9] 71.4 [58.8-80.8] 74.6 [69.6-79.0] 73.2 [69.7-76.4]  
VIII.a Osteosarcomas 100.0 [-] 51.9 [22.5-75.0] 70.4 [62.2-77.2] 71.6 [66.6-76.0]  
VIII.c Ewing tumors and related bone sarcomas 66.7 [5.4-94.5] 75.7 [61.1-85.5] 77.0 [69.7-82.7] 73.0 [67.3-77.9]  
IX. Soft tissue and other extraosseous sarcomas 70.2 [62.7-76.5] 73.8 [69.5-77.5] 74.0 [69.4-77.9] 68.5 [64.0-72.6]  
IX.a Rhabdomyosarcomas 83.2 [69.9-90.9] 74.9 [70.1-79.1] 71.7 [65.7-76.8] 62.8 [54.4-70.1] **
IX.b Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 90.0 [77.5-95.7] 90.9 [50.8-98.7] 74.9 [45.6-89.9] 57.0 [39.0-71.6] **
IX.d Other specified soft tissue sarcomas 38.8 [25.7-51.8] 72.4 [61.8-80.4] 79.6 [71.0-85.8] 73.4 [67.0-78.7] **
IX.e Unspecified soft tissue sarcomas 63.5 [33.1-83.0] 44.7 [21.8-65.4] 69.5 [49.1-83.1] 71.9 [57.1-82.4]  
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads 91.1 [86.6-94.2] 95.8 [91.7-97.9] 96.8 [91.8-98.8] 92.8 [89.7-95.0]  
X.a Intracranial and intraspinal germ cell tumors 90.0 [72.0-96.7] 92.5 [83.0-96.8] 95.6 [86.9-98.6] 94.3 [89.7-96.9]  
X.b Malignant extracranial and extragonadal germ cell tumors 89.1 [83.0-93.1] 95.6 [86.8-98.5] 100.0 [-] 84.8 [64.2-94.0]  
X.c Malignant gonadal germ cell tumors 100.0 [-] 100.0 [-] 100.0 [-] 95.1 [90.4-97.5]  
XI. Other malignant epithelial neoplasms and malignant melanomas 96.4 [77.2-99.5] 86.7 [76.6-92.6] 92.7 [87.5-95.8] 93.2 [90.6-95.1]  
XI.b Thyroid carcinomas 100.0 [-] 100.0 [-] 98.6 [90.5-99.8] 98.7 [96.0-99.6]  
XI.d Malignant melanomas 100.0 [-] 76.7 [52.5-89.7] 89.5 [74.3-95.9] 88.9 [79.6-94.1]  
XII. Other and unspecified malignant neoplasms 90.0 [47.3-98.5] 78.6 [58.4-89.8] 85.7 [33.4-97.9] 55.6 [20.4-80.5]  
All cancers (excluding LCH) 81.0 [79.4-82.4] 82.4 [81.6-83.2] 81.7 [80.7-82.6] 83.0 [82.1-83.9] **
Langherhans cell histiocytosis 87.0 [73.2-93.9] 95.9 [84.7-99.0] 100.0 [-] 100.0 [-]  
All cancers (including LCH) 81.1 [79.5-82.5] 82.5 [81.7-83.3] 81.7 [80.7-82.7] 83.0 [82.1-83.9] **

p : pvalue of the logrank test (* <0.05; ** < 0.01)

5-year overall survival rates of childhood cancer in mainland France over 2000-2014, by diagnostic and age groups

Villejuif

INSERM
UMRS1153 Equipe 7
Bâtiment 15/16
16 avenue Paul Vaillant Couturier
94807 Villejuif Cedex

+33 (0)1 45 59 50 37
rnhe@inserm.fr

Nancy

Faculté de Médecine
BP 20199
9 avenue de la Forêt de Haye
54505 Vandoeuvre les Nancy Cedex

+33 (0)3 72 74 63 26
rntse@inserm.fr