Overall incidence estimation
For the 2010-2014 period, 8,890 cancer cases have been registered in the RNCE database. The standardised incidence rate is 156 cases per million children per year, representing about 1,780 new cases diagnosed in France each year, in children under 15 years.
The distribution of cancer type by histological type and cancer site in children differs significantly from that in adults, with noticeably fewer carcinomas diagnosed in children. This is the reason why childhood cancers are categorised according to a specific paediatric classification: the International Classification of Childhood Cancer (ICCC), 3rd revision.
Table 1 shows the distribution of the 12 main childhood cancer groups, and the incidence for the period 2010-2014. Table 2 provides more detail on the distribution by age group.
In France, childhood cancer incidence has remained stable over the 2000-2014 period for all cancers (average annual percent change AAPC =0.1% [-0.3%; 0.2%], and for the various diagnostic groups (table 3).