Registre National des Cancers de l’Enfant

5-year overall survival rates of childhood cancer in mainland France, by diagnostic groups and periods

Diagnostic groups and subgroups   2000-2004       2005-2009       2010-2014   P
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases 83.0 [81.4-84.4] 87.1 [85.6-88.3] 86.0 [84.3-87.5] **
I.a Lymphoid leukemias 89.2 [87.7-90.5] 91.0 [89.6-92.2] 88.4 [86.6-90.0] *
I.b Acute myeloid leukemias 59.4 [54.3-64.1] 71.6 [66.4-76.2] 76.4 [71.1-80.8] **
II. Lymphomas and reticuloendothelial neoplasms 93.5 [91.7-94.8] 93.1 [91.3-94.6] 95.6 [93.9-96.8]  
II.a Hodgkin lymphomas 96.7 [94.5-98.0] 96.7 [94.3-98.0] 99.1 [97.3-99.7]  
II.b Non-Hodgkin lymphomas (except Burkitt lymphomas) 90.9 [87.0-93.7] 86.6 [82.0-90.1] 90.3 [85.9-93.4]  
II.c Burkitt lymphomas 91.4 [87.2-94.2] 95.1 [91.4-97.3] 96.0 [92.2-98.0]  
III. CNS and miscellaneous intracranial and intraspinal neoplasms 70.8 [68.8-72.8] 74.5 [72.6-76.4] 74.1 [72.0-76.1] *
III.a Ependymomas and choroid plexus tumors 62.2 [55.0-68.6] 77.1 [70.6-82.3] 83.3 [76.3-88.4] **
III.b Astrocytomas 86.9 [84.3-89.1] 87.9 [85.3-90.0] 83.2 [80.2-85.8] *
III.c Intracranial and intraspinal embryonal tumors 52.2 [47.3-56.9] 55.3 [50.3-6.0] 55.3 [49.4-60.9]  
III.d Other gliomas 34.9 [29.3-40.5] 39.7 [34.2-45.1] 39.2 [33.1-45.3]  
III.e Other specified intracranial and intraspinal neoplasms 93.5 [90.3-95.7] 95.8 [93.3-97.3] 94.8 [91.6-96.8]  
IV. Neuroblastomas and other peripheral nervous cell tumors 72.8 [69.3-75.9] 75.4 [72.0-78.4] 78.8 [75.0-82.2]  
IV.a Neuroblastomas and ganglioneuroblastomas 72.6 [69.1-75.8] 75.2 [71.8-78.2] 78.7 [74.7-82.1]  
V. Retinoblastomas 99.2 [96.8-99.8] 98.5 [96.0-99.4] 100.0 [-]  
VI. Renal tumors 91.8 [89.0-94.0] 93.0 [90.4-94.9] 94.1 [91.2-96.1]  
VI.a Nephroblastomas and other nonepithelial renal tumors 92.1 [89.2-94.2] 93.0 [90.3-94.9] 94.2 [91.3-96.2]  
VII. Hepatic tumors 83.1 [72.2-90.0] 79.1 [69.5-86.0] 82.6 [71.7-89.5]  
VII.a Hepatoblastomas 88.3 [77.1-94.3] 82.0 [71.6-88.9] 82.1 [71.1-89.2]  
VIII. Malignant bone tumors 74.6 [70.0-78.6] 75.6 [71.1-79.,5] 69.1 [63.0-74.5]  
VIII.a Osteosarcomas 72.9 [66.1-78.5] 74.5 [67.4-80.3] 63.1 [53.7-71.1]  
VIII.c Ewing tumors and related bone sarcomas 74.7 [67.4-80.6] 74.4 [67.6-79.9] 75.4 [66.7-82.1]  
IX. Soft tissue and other extraosseous sarcomas 69.1 [65.0-72.8] 73.5 [69.6-76.9] 73.5 [68.6-77.7]  
IX.a Rhabdomyosarcomas 67.4 [61.6-72.4] 74.2 [68.9-78.7] 77.1 [70.7-82.4]  
IX.b Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 74.4 [57.6-85.3] 80.0 [64.0-89.5] 76.9 [56.8-88.5]  
IX.d Other specified soft tissue sarcomas 72.5 [65-78.7] 71.3 [63.9-77.4] 67.9 [58.6-75.7]  
IX.e Unspecified soft tissue sarcomas 60.0 [43.2-73.3] 70.5 [53.9-82.1] 69.1 [49.5-82.3]  
X. Germ-cell tumors, trophoblastic tumors, and neoplasms of gonads 92.3 [89.0-94.7] 93.1 [89.8-95.4] 96.4 [93.5-98.1]  
X.a Intracranial and intraspinal germ cell tumors 91.9 [85.5-95.6] 94.0 [87.9-97.1] 96.5 [90.9-98.7]  
X.b Malignant extracranial and extragonadal germ cell tumors 92.3 [84.5-96.3] 85.2 [76.3-91.0] 96.2 [88.6-98.7]  
X.c Malignant gonadal germ cell tumors 95.7 [89.9-98.2] 98.3 [93.2-99.6] 98.6 [90.2-99.8]  
XI. Other malignant epithelial neoplasms and malignant melanomas 92.5 [88.6-95.1] 93.2 [89.5-95.7] 91.4 [86.7-94.5]  
XI.b Thyroid carcinomas 98.2 [93.0-99.5] 100.0 [-] 96.9 [86.7-99.3]  
XI.d Malignant melanomas 83.6 [70.8-91.1] 86.8 [72.8-93.8] 94.2 [83.1-98.1]  
XII. Other and unspecified malignant neoplasms 57.1 [28.4-78.0] 89.5 [64.1-97.3] 81.5 [57.9-92.6]  
All cancers (excluding LCH) 80.8 [79.9-81.6] 83.3 [82.4-84.0] 83.1 [82.1-84.0] **
Langherhans cell histiocytosis (LCH) 94.4 [79.6-98.6] 97.1 [80.9-99.6] 85.2 [68.0-93.6]  
All cancers (including LCH) 80.8 [80.0-81.6] 83.3 [82.5-84.1] 83.1 [82.1-84.0] **

p : pvalue of the logrank test (* <0.05; ** < 0.01)

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